Cast Charming Scoundrel either from your hand or from the top of your library by paying 2.
When Charming Scoundrel enters the battlefield, it triggers, creating a Wicked Role token attached to it.
Activate Ashnod's Altar by sacrificing Charming Scoundrel, adding 2.
Charming Scoundrel is returned to your hand instead of being put into your graveyard due to Necromancer's Magemark.
The Wicked Role token that was attached to Charming Scoundrel triggers, causing each opponent to lose 1 life.
Repeat.
This clever loop turns Charming Scoundrel into an endless cycle of sacrifice and rebirth, fueled by Ashnod's Altar providing the exact {2} mana needed to recast it. Necromancer's Magemark provides the crucial replacement effect that bounces Charming Scoundrel back to your hand instead of the graveyard whenever it dies, while simultaneously ensuring its Wicked Role token triggers the moment it leaves the battlefield to drain your opponents out. Meanwhile, Vizier of the Menagerie lets you streamline the entire engine by casting Charming Scoundrel directly from the top of your library, turning a modest rogue into an infinite storm of enters-the-battlefield and sacrifice triggers.