Staff of Domination + Cryptic Trilobite + Cleric Class + Heliod, Sun-Crowned
Staff of Domination
Cryptic Trilobite
Cleric Class
Heliod, Sun-Crowned
Infinite lifegain triggersInfinite lifegainInfinite card drawInfinite untap of creatures you controlInfinite draw triggersInfinite mana creatures you control can produceInfinite colorless mana that can only be spent to activate abilities
How it works
Activate Staff of Domination's second ability by paying 2 and tapping it, causing you to gain 2 life.
Cleric Class and Heliod trigger, putting two +1/+1 counters on Cryptic Trilobite.
Activate Cryptic Trilobite twice by removing two +1/+1 counters from it, adding CCCC that can only be spent to activate abilities.
Activate Staff of Domination's first ability by paying 1, untapping it.
Repeat.
This intricate loop transforms a simple life-gain activation into an engine of endless possibilities. By paying two mana into Staff of Domination to gain life, you trigger both Cleric Class and Heliod, Sun-Crowned, which combine to place multiple +1/+1 counters back onto Cryptic Trilobite. You can then strip those very counters away using Cryptic Trilobite's ability to generate the specialized mana needed to untap Staff of Domination and repeat the entire sequence. Because the Staff also holds abilities to draw cards and untap creatures, fueling this loop indefinitely cascades into an overwhelming advantage across your entire board.