Anhelo, the Painter + Twinning Staff + Repeated Reverberation + Prologue to Phyresis

Anhelo, the Painter

Twinning Staff

Repeated Reverberation

Prologue to Phyresis

How it works

1. Cast Repeated Reverberation by paying 2 and sacrificing a creature with power two or greater.
2. Repeated Reverberation's casualty ability triggers, creating two copies of it due to Twinning Staff.
3. Resolve each Repeated Reverberation, causing you to copy the next instant or sorcery spell you cast six times.
4. Cast Prologue to Phyresis by paying 1.
5. Each Repeated Reverberation triggers, copying Prologue to Phyresis a total of nine times due to Twinning Staff.
6. Resolve each Prologue to Phyresis, causing each opponent to get ten poison counters, and you to draw ten cards.
7. Each opponent loses the game due to having ten or more poison counters.