Mindslaver + Volrath's Dungeon

Mindslaver

Volrath's Dungeon

How it works

1. Cast Volrath's Dungeon for 2.
2. Target the opponent who's turn is after yours with Mindslaver.
3. On their turn, force them to pay 5 life to destroy Volrath's Dungeon while holding priority.
4. With the destroy trigger on the stack, repeat this process until they have 0 life.

This deliciously cruel loop relies on Mindslaver to seize the reins of your opponent's turn, turning their own resources against them. While you're in the driver's seat, you use Volrath's Dungeon to repeatedly force them into paying 5 life to destroy the enchantment itself. Because you control all of their decisions, you can drain their life total down to zero before they can even blink, all while safely ignoring the enchantment's discard ability.