Mindslaver + Lethal Vapors + Tidal Barracuda

Mindslaver

Lethal Vapors

Tidal Barracuda

How it works

1. Activate Mindslaver by paying 4, tapping and sacrificing it, causing you to gain control of target opponent during their next turn.
2. During the opponent's turn, cast Lethal Vapors by paying 2.
3. As the opponent, activate Lethal Vapors by paying 0 an arbitrarily large number of times, causing that opponent to skip that many turns.

This insidious lock hinges entirely on turning your opponent's own resources against them by taking the helm with Mindslaver. Once you're in the driver's seat, Tidal Barracuda steps in to grant flash so you can cast Lethal Vapors right during that controlled turn, bypassing normal timing restrictions. Finally, the opponent uses Lethal Vapors' own self-destruct activation any number of times to pile up skipped turns, effectively writing them out of the rest of the game entirely.