Syr Konrad, the Grim + Tainted Strike + Elixir of Immortality

Syr Konrad, the Grim

Tainted Strike

Elixir of Immortality

How it works

1. Cast Tainted Strike by paying , giving Syr Konrad +1/+0 and infect until end of turn.
2. Activate Elixir of Immortality by paying 2 and tapping it, causing you to gain 5 life and shuffle Elixir of Immortality and your graveyard into your library.
3. Syr Konrad triggers for each creature card that left your graveyard this way, giving each opponent that many poison counters.
4. Each opponent loses the game due to having ten or more poison counters.

This cunning setup turns a simple life-gain artifact into a lethal win condition by weaponizing the rules of zone changes. While Elixir of Immortality is normally just used to buffer your life total and recycle your graveyard, shuffling those cards away causes Syr Konrad, the Grim to trigger for every single creature card that leaves your graveyard. Because Tainted Strike has already granted Syr Konrad the infect keyword, all of that non-combat damage is converted instantly into poison counters. The result is an overwhelming, game-ending storm of toxic damage that bypasses your opponents' life totals entirely.