Isochron Scepter + Final Fortune + Obeka, Brute Chronologist

Isochron Scepter

Final Fortune

Obeka, Brute Chronologist

How it works

1. Activate Isochron Scepter by paying 2, casting a copy of Final Fortune.
2. At the beginning of your next end step, if you cast Final Fortune on the previous turn, Final Fortune's lose the game ability triggers.
3. In response, activate Obeka by tapping it, choosing to end the turn and exiling the stack in the process.
4. Repeat each turn.