Anti-Venom, Horrifying Healer + Agatha's Soul Cauldron + Triskelion + City on Fire

Anti-Venom, Horrifying Healer

Agatha's Soul Cauldron

Triskelion

City on Fire

How it works

1. Activate Anti-Venom using Triskelion's ability by removing a +1/+1 counter from it, targeting itself and putting three +1/+1 counters on it due to its replacement effect and City on Fire.
2. Activate Anti-Venom using Triskelion's ability by removing a +1/+1 counter from it, dealing 1 damage to any target.
3. Repeat.

This clever loop turns Anti-Venom, Horrifying Healer into a self-sustaining artillery piece by utilizing Agatha's Soul Cauldron to grant him the activated ability of an exiled Triskelion. Because Anti-Venom's replacement effect prevents damage dealt to him and converts it into matching +1/+1 counters instead, every ping directed at himself instantly reloads his ammunition with interest. This explosive output is pushed to devastating heights by City on Fire, whose passive damage-tripling effect ensures that every activation generates a surplus of counters to sustain the loop indefinitely while wiping out any target you choose.