Anti-Venom, Horrifying Healer + Agatha's Soul Cauldron + Triskelion + Fiery Emancipation

Anti-Venom, Horrifying Healer

Agatha's Soul Cauldron

Triskelion

Fiery Emancipation

How it works

1. Activate Anti-Venom using Triskelion's ability by removing a +1/+1 counter from it, targeting itself and putting three +1/+1 counters on it due to its replacement effect and Fiery Emancipation.
2. Activate Anti-Venom using Triskelion's ability by removing a +1/+1 counter from it, dealing 1 damage to any target.
3. Repeat.

This intricate loop turns self-inflicted harm into an unstoppable engine of destruction by combining damage-redirection with damage-tripling. With Agatha's Soul Cauldron exiling Triskelion and granting its activated ability to creatures you control, Anti-Venom, Horrifying Healer gains the power to ping targets by removing its own counters. Because Fiery Emancipation triples the 1 damage that Anti-Venom tries to deal to itself, its own replacement effect steps in to prevent that damage and instead reward it with three +1/+1 counters. This leaves you with a net gain of counters to continually fuel the loop for infinite damage.