Anti-Venom, Horrifying Healer + Agatha's Soul Cauldron + Triskelion + Winding Constrictor

Anti-Venom, Horrifying Healer

Agatha's Soul Cauldron

Triskelion

Winding Constrictor

How it works

1. Activate Anti-Venom using Triskelion's ability by removing a +1/+1 counter from it, targeting itself and putting two +1/+1 counters on it due to its replacement effect and Winding Constrictor.
2. Activate Anti-Venom using Triskelion's ability by removing a +1/+1 counter from it, dealing 1 damage to any target.
3. Repeat.

This loop is a masterclass in turning self-inflicted harm into lethal force, fueled by Agatha's Soul Cauldron exiling Triskelion to grant its activated ability to Anti-Venom, Horrifying Healer. Because Anti-Venom's damage-prevention ability converts incoming damage into +1/+1 counters instead, shooting it with its own borrowed Triskelion ping actually grows it rather than destroying it. Winding Constrictor supercharges this exchange by adding an extra counter every time one is placed, turning the damage-into-counters conversion net-positive and allowing you to loop the process indefinitely for infinite damage and infinite growth.