Anti-Venom, Horrifying Healer + Agatha's Soul Cauldron + Triskelion + Quest for Pure Flame

Anti-Venom, Horrifying Healer

Agatha's Soul Cauldron

Triskelion

Quest for Pure Flame

How it works

1. Activate Quest for Pure Flame by removing four quest counters from it and sacrificing it, doubling the damage sources you control will deal this turn.
2. Activate Anti-Venom using Triskelion's ability by removing a +1/+1 counter from it, targeting itself and putting two +1/+1 counters on it due to its replacement effect and Quest for Pure Flame.
3. Activate Anti-Venom using Triskelion's ability by removing a +1/+1 counter from it, dealing 1 damage to any target.
4. Repeat from step 2.

This loop starts by cracking Quest for Pure Flame to double all damage your sources deal, laying the groundwork for an explosive finish. You use Agatha's Soul Cauldron to exile Triskelion and grant its activated ability to Anti-Venom, Horrifying Healer, who now has the power to fling damage at will. Because Anti-Venom prevents any damage dealt to it and replaces it with an equal number of +1/+1 counters—which are further doubled by Quest for Pure Flame—shooting Anti-Venom with its own acquired Triskelion ability generates a net gain of counters. You can then use those extra counters to deal infinite damage to any target, wiping out opponents and their boards in one fell swoop.