Jace, Wielder of Mysteries + Phyrexian Unlife + Spoils of the Vault

Jace, Wielder of Mysteries

Phyrexian Unlife

Spoils of the Vault

How it works

1. Cast Spoils of the Vault by paying , naming any card not in your library, exiling your entire library and losing life equal to the number of cards exiled this way.
2. Activate Jace's first loyalty ability by putting a loyalty counter on it, causing target player to mill two cards and you to win the game due to drawing from an empty library.