Activate Lithatog's first ability by sacrificing Ugin's Nexus, giving it +1/+1 until end of turn.
When Ugin's Nexus is sacrificed, it is exiled instead of being put into your graveyard, causing you to take an extra turn after this one.
Move to your next turn.
Activate Isochron Scepter by paying 2 and tapping it, casting a copy of Pull from Eternity without paying its mana cost.
Resolve Pull from Eternity, putting Ugin's Nexus from exile into your graveyard.
Deal combat damage to an opponent using an Assassin, triggering Layla Hassan, returning Ugin's Nexus from your graveyard to your hand.
Cast Ugin's Nexus by paying 5.
Repeat.
This intricate loop seizes infinite turns by weaponizing Ugin's Nexus's replacement effect, which both grants an extra turn and exiles itself when put into a graveyard. To bypass that exile permanently, Isochron Scepter imprints Pull from Eternity to snatch the Nexus right back into the graveyard, while Layla Hassan leverages an Assassin's combat damage to return it cleanly to your hand. Meanwhile, Lithatog acts as the crucial sacrifice outlet to send the Nexus away on command, letting you recast it and repeat the cycle endlessly.