Necromancer's Magemark + Charming Scoundrel + Ashnod's Altar + Mycosynth Lattice

Necromancer's Magemark

Charming Scoundrel

Ashnod's Altar

Mycosynth Lattice

How it works

1. Cast Charming Scoundrel by paying 2.
2. When Charming Scoundrel enters the battlefield, it triggers, creating a Wicked Role token attached to it.
3. Activate Ashnod's Altar by sacrificing Charming Scoundrel, adding 2.
4. Charming Scoundrel is returned to your hand instead of being put into your graveyard due to Necromancer's Magemark.
5. The Wicked Role token that was attached to Charming Scoundrel triggers, causing each opponent to lose 1 life.
6. Repeat.

This clever loop turns the humble Charming Scoundrel into an endless engine of sacrifice and life loss by rewriting the rules of the battlefield with Mycosynth Lattice. Because the Lattice makes all permanents into artifacts, Ashnod's Altar eagerly accepts any creature sacrifice to fuel your mana pool, while Necromancer's Magemark protects your enchanted threats by bouncing them straight back to your hand instead of the graveyard whenever they die. As you recast the Scoundrel, its entrance triggers a Wicked Role token that continually drains your opponents' life totals, creating an infinite loop of death and rebirth.