Etrata, the Silencer + The Peregrine Dynamo + Strionic Resonator

Etrata, the Silencer

The Peregrine Dynamo

Strionic Resonator

How it works

1. Deal combat damage to an opponent using Etrata, triggering its ability.
2. Holding priority, activate Strionic Resonator and The Peregrine Dynamo by paying 3 and tapping them, copying Etrata's trigger twice.
3. Resolve all Etrata triggers, exiling three creatures an opponent controls and putting hit counters on them, and then causing that opponent to lose the game.