Etrata, the Silencer + Strionic Resonator + Lithoform Engine

Etrata, the Silencer

Strionic Resonator

Lithoform Engine

How it works

1. Deal combat damage to an opponent using Etrata, triggering its ability.
2. Holding priority, activate Lithoform Engine and Strionic Resonator by paying 4 and tapping them, copying Etrata's trigger twice.
3. Resolve all Etrata triggers, exiling three creatures an opponent controls and putting hit counters on them, and then causing that opponent to lose the game.