Etrata, the Silencer + Lithoform Engine + Adric, Mathematical Genius

Etrata, the Silencer

Lithoform Engine

Adric, Mathematical Genius

How it works

1. Deal combat damage to an opponent using Etrata, triggering its ability.
2. Holding priority, activate Adric and Lithoform Engine by paying 4 and tapping them, copying Etrata's trigger twice.
3. Resolve all Etrata triggers, exiling three creatures an opponent controls and putting hit counters on them, and then causing that opponent to lose the game.

This elegant assassination engine relies on unblockable combat damage from Etrata, the Silencer to trigger her lethal exile effect all in a single devastating strike. As her damage trigger goes on the stack, you can tap both Adric, Mathematical Genius and Lithoform Engine to pay their respective costs and multiply that single trigger into three. With all three instances resolving, your opponent is forced to watch as three of their creatures are exiled with hit counters, instantly fulfilling Etrata's alternate win condition and securing the game.