Activate Lonis by paying 2 and sacrificing another artifact.
If the artifact was a Clue, Lonis' third ability triggers, putting two +1/+1 counters on any other creature you control.
Resolve the Lonis ability, putting two +1/+1 counters on it and causing you to draw a card.
Lonis' second ability triggers, creating four Clue artifact tokens.
Activate Krark-Clan Ironworks by sacrificing a Clue, adding CC.
Lonis' third ability triggers, putting two +1/+1 counters on any other creature you control.
Repeat.
This clever synergy transforms Clues from mere drawing tools into a self-sustaining engine of growth and resources. Clan Crafter grants the crucial activated ability that lets you sacrifice artifacts for a counter and a card, which sets Lonis, Genetics Expert into motion by triggering investigations every time counters are added. Meanwhile, Krark-Clan Ironworks provides an alternative sacrifice outlet that feeds you colorless mana to keep the loop going, and Primal Vigor supercharges the entire operation by doubling both the tokens created and the counters distributed.