Ad Nauseam + Angel's Grace + Skirge Familiar + Pestilence

Ad Nauseam

Angel's Grace

Skirge Familiar

Pestilence

How it works

1. Cast Angel's Grace by paying , preventing you from losing the game this turn.
2. Cast Ad Nauseum by paying 3, putting your entire library in your hand and losing life equal to the total converted mana cost of those cards.
3. Activate Skirge Familiar many times by discarding your entire hand, adding for each card discarded.
4. Actviate Pestilence many times by paying each time, dealing 1 damage to each creature and each player each time.