Skirk Fire Marshal + Blessed Sanctuary + Tainted Strike

Skirk Fire Marshal

Blessed Sanctuary

Tainted Strike

How it works

1. Cast Tainted Strike by paying , giving Skirk Fire Marshal +1/+0 and infect until end of turn.
2. Activate Skirk Fire Marshal by tapping five untapped Goblins, giving each opposing creature ten -1/-1 counters and giving each opponent ten poison counters.
3. Each opponent loses the game as a state-based action due to having ten poison counters.