Activate Lonis by paying 2 and sacrificing another artifact.
If the artifact was a Clue, Lonis' third ability triggers, putting a +1/+1 counter on any other creature you control.
Resolve the Lonis ability, putting a +1/+1 counter on it and causing you to draw a card.
Lonis' second ability triggers, creating a Clue, a Food and a Treasure artifact token.
Activate Krark-Clan Ironworks by sacrificing any of the artifact tokens, adding CC.
If the artifact was a Clue, Lonis' third ability triggers, putting a +1/+1 counter on any other creature you control.
Repeat.
This delightful loop turns the humble act of cracking clues into a self-sustaining engine of growth and resources. Clan Crafter grants Lonis, Genetics Expert the ability to sacrifice an artifact for a counter and a card, which in turn triggers Lonis to spit out Clues. But the real magic happens because Academy Manufactor transforms every single Clue creation into a trio of Clue, Food, and Treasure tokens, giving you plenty of fodder to feed into Krark-Clan Ironworks. By turning those extra manufactured artifacts into raw colorless mana, you can continually pay for Clan Crafter's activation cost while continuously triggering Lonis, Genetics Expert to snowball your board into infinite tokens and card draw.