This clever loop centers around the unique replacement effect of Vizier of Remedies, which turns the single -1/-1 counter that would normally be placed by persist into zero counters at all. Because Heartmender returns to the battlefield with a completely clean slate, its persist ability can trigger indefinitely every time it is sacrificed. Phantom Train acts as the engine for this loop, letting you feed Heartmender to its sacrifice ability to grow the Train with infinite +1/+1 counters while generating endless entry, death, and sacrifice triggers.