Chains of Mephistopheles + Bone Miser + Shenanigans
Chains of Mephistopheles
Bone Miser
Shenanigans
Infinite self-mill
How it works
Attempt to draw a card. The draw will be replaced by Chains of Mephistopheles, causing you to instead discard Shenanigans. Then, you will mill a card and return Shenanigans from your graveyard to your hand due to Shenanigans's dredge ability.
Bone Miser's third ability triggers, attempting to have you draw a card. The draw will be replaced by Chains of Mephistopheles, causing you to instead discard Shenanigans. Then, you will mill a card and return Shenanigans from your graveyard to your hand due to Shenanigans's dredge ability.