Captain Sisay + Mindslaver + Wheel of Sun and Moon
Captain Sisay
Mindslaver
Wheel of Sun and Moon
You control one opponent on their turn each turn cycleLock
How it works
Activate Mindslaver by paying 4, tapping and sacrificing it.
Mindslaver is put onto the bottom of your library instead of into your graveyard due to Wheel of Sun and Moon.
Resolve the Mindslaver ability, causing you to gain control of target opponent during their next turn.
During your next turn, activate Captain Sisay by tapping it, searching your library for Mindslaver and putting it into your hand.
Cast Mindslaver by paying 6.
Repeat.
This vicious lock completely strips your opponents of their agency by exploiting the replacement effect of Wheel of Sun and Moon. When you sacrifice Mindslaver to take control of a player, Wheel of Sun and Moon neatly rescues the artifact from your graveyard and tucks it safely onto the bottom of your library instead. From there, you simply use Captain Sisay's tutor ability on your turn to fetch Mindslaver right back into your hand, ready to be recast and repeated every single turn cycle.