Simic Ascendancy + Master Biomancer + Colossus Hammer + Belt of Giant Strength

Simic Ascendancy

Master Biomancer

Colossus Hammer

Belt of Giant Strength

How it works

1. Cause another creature to enter the battlefield under your control with at least 20 +1/+1 counters on it due to Master Biomancer.
2. Simic Ascendancy's second ability triggers, putting 20 growth counters on Simic Ascendancy.
3. At the beginning of your next upkeep, Simic Ascendancy's third ability triggers, causing you to win the game.

This elegant loop transforms a massive equipment-stuffed creature into an immediate alternate-win condition. By stacking the power-boosting effects of Colossus Hammer and Belt of Giant Strength onto a creature, Master Biomancer scales up exponentially so that the next creature entering your battlefield arrives bearing at least twenty +1/+1 counters. That influx of counters instantly triggers Simic Ascendancy, loading it with twenty growth counters in a single stroke and setting you up to claim the game at the very start of your next upkeep.