Windfall + Fate Unraveler + Triumph of the Hordes

Windfall

Fate Unraveler

Triumph of the Hordes

How it works

1. Cast Triumph of the Hordes by paying 2, giving creatures you control infect until end of turn.
2. Cast Windfall by paying 2, causing each player to discard their hand and then draw a number of cards equal to the greatest number of cards a player discarded this way.
3. Fate Unraveler triggers for each card drawn this way, giving each opponent a poison counter for each card they drew.
4. Each opponent loses the game due to having ten or more poison counters