Academy Manufactor + Pitiless Plunderer + Cauldron Familiar + Woe Strider

Academy Manufactor

Pitiless Plunderer

Cauldron Familiar

Woe Strider

How it works

1. Activate Woe Strider by sacrificing Cauldron Familiar
2. When Cauldron Familar dies, Pitiless Plunderer triggers, creating a Food, a Clue, and a Treasure token.
3. Resolve the Woe Strider ability.
4. Activate Cauldron Familiar by sacrificing a Food, returning Cauldron Familiar from your graveyard to the battlefield.
5. When Cauldron Familiar enters the battlefield, it triggers, causing each opponent to lose 1 life and you to gain 1 life.
6. Repeat.