This loop relies on Trapjaw Kelpie entering and leaving the battlefield repeatedly, fueled by the sacrifice outlet Thermopod which converts each iteration into a steady stream of red mana. Ordinarily, the persist ability would place a -1/-1 counter on Trapjaw Kelpie upon its return, permanently shutting down the loop after a single use. However, Vizier of Remedies completely neutralizes that drawback by reducing the applied -1/-1 counters to zero, allowing Trapjaw Kelpie to return pristine and ready to be sacrificed all over again.