This clever loop turns Glen Elendra Archmage into an endlessly recurring counterspell engine by leaning on the replacement effect of Vizier of Remedies, which prevents the persist ability from ever permanently stalling out with a -1/-1 counter. Whenever you need to clear the stack, you simply sacrifice the Archmage to Bloodflow Connoisseur; persist brings her right back with a clean slate, ready to counter another noncreature spell while simultaneously pumping the Connoisseur full of infinite +1/+1 counters. It is a wonderfully efficient way to lock down the board and dominate your opponents using sacrifice and death synergies.